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A comment on WASF3 disrupts mitochondria and may mediate exercise intolerance in CFS.

Re:WASF3 disrupts mitochondria and may mediate exercise into... by joshjhargreaves on Wednesday August 16, 2023 @12:31PM (#37149572)
All I can say is that having significant gut dysbiosis is enough to have significant fatigue - think for sure, you can end up having fatigue from cell energy production issues, but it's clear to me that there are definitely different causes of CFS.
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Re:WASF3 disrupts mitochondria and may mediate exercise into... by vaelin on Tuesday August 22, 2023 @11:57AM (#37224585)
It's possibly the same thing. Endoplasmic Reticulum Stress, the type of stress which may cause this protein to become elevated, was induced in mice by exposing them to endotoxin, a type of toxin produced in the gut.

So gut dysbiosis may trigger this very mechanism.

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