I wouldn't call Nature or Science a crown jewel of research publications at this point. I can't remember the last time they published anything decent in a field I (or someone I know) is familiar with. In fact, the articles I'm thinking of ended up being retracted or refuted pretty quickly.

Being published in them is a good way to get social media karma though. Some people even manage leverage the article to get a tenured position somewhere (often to their future students' peril).

I follow the physical sciences (by education,) astronomy/astrophysics (by interest,) and biology and earth science as time permits. As far as I can tell, Science and Nature still get topnotch stuff.

As a Science subscriber I try hard to make time to read papers well out of my expertise. I start with the research summary article (by an independent writer) for context before going to the full paper. I figure if it made it to press there, it is worth my time to figure out what makes it important to that field.

I still get invited to random overseas "conferences" vaguely related to work I did. I left academia almost a decade ago, although I still have co-authorship on some recent publications from my old group.

After getting my second co-authored paper published during my time as an undergrad in relatively high-impact journals, I started getting spammed with requests to review shady COVID-19 related manuscripts by no-name journals.

The amount of damage shitty articles and shitty journals out there is terrifying to think about.