My understanding, sorry for not having links at the ready for all this, is that many studying this currently think that Cro Magons, Neanderthals, and Denisovans all mixed to varying degrees at various times and emerged from a complex mix of pre humans like Homo Naledi. This makes the ancestry of Homo Sapiens more complex than simple lines of descent. Genetic analysis of these groups suggests that there was a third group that mixed with Neanderthals and Denisovans which has not yet been identified. None of this relates to the multiregion origin theory that you mention.