lossless? large sizes? multi-band (> 3) data? transparency? animation? I work in software support of scientific imaging, and jpeg-xl looks to be the only format to date that supports those features in addition to excellent compression and royalty-free licenses (we currently use jpeg-2000 which has no good/fast open-source implementation, we really on an expensive proprietary license with lots of restrictions on redistribution, in fact our industry is largely moving back to TIFF now with the storage factors you mentioned, but using 10x the disk space is non-trivial).