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A comment on Scientists May Have Found Mechanism Behind Cognitive Decline in Aging. Parent comment

Re:Scientists May Have Found Mechanism Behind Cognitive Decl... by ekianjo on Sunday July 30, 2023 @06:08AM (#36929619)
Aspirin is famous for having teratogenic effects on rabbits and would never have been approved for humans if it were to be tested nowadays
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Re:Scientists May Have Found Mechanism Behind Cognitive Decl... by haldujai on Sunday July 30, 2023 @11:17AM (#36932047)
Why? Plenty of teratogenic drugs are approved and in routine use in non-pregnant patients.
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Re:Scientists May Have Found Mechanism Behind Cognitive Decl... by ekianjo on Sunday July 30, 2023 @01:47PM (#36933906)
Any recent example?
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Re:Scientists May Have Found Mechanism Behind Cognitive Decl... by haldujai on Sunday July 30, 2023 @02:23PM (#36934343)
Not really sure what you're getting at, teratogenicity only matters if a person is pregnant and lack of teratogenicity is in no way a requirement for FDA approval.

There are many commonly used drugs with teratogenic risks that we discontinue in pregnancy or counsel the patient on, picking randomly from a list of medications that were approved in 2023: sparsentan

I'm not sure if I'm missing something but why are you thinking teratogenicity matters when the vast majority of patients are not pregnant at a given moment?

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