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Re:Enjoy Alcohol, Without the Hangover by AuryGlenz on Saturday July 29, 2023 @10:59AM (#36920918)
Synthehol. It’s never really fully explained how it affects you other than you can kind of readily shake it off.

There are plenty of instances in Star Trek of people drinking the real stuff though. Picard himself had a family winery. I’m guessing he was amazed at a bottle of Romulan Ale, which was illegal in the same way Cuban cigars were here.

Re:Enjoy Alcohol, Without the Hangover by ben_w on Saturday July 29, 2023 @11:18AM (#36921095)
In the show, Romulan Ale is also extremely strong; Worf nurses a hangover from it and says it "should be illegal" and LaForge replies "It is"; while in DS9 several of the human main cast infiltrated a Klingon event and had to take something to avoid dying from drinking so much Blood Wine.

(That said, I don't know if it's been canonically stated Blood Wine is ethanol based, so future writers might just decide that's because Blood Wine is based on methanol rather than ethanol, and the ABV is unsurprising…)