From the article: "This breakthrough, which earned a Nobel Prize, prompted scientists to question if cellular aging could be reversed without pushing cells to become too young and potentially cancerous."

It may have already been solved with _partial_ epigenetic reprogramming with Yamanaka or related factors, where _partial_ means do not pushing cells all the way back to embryonic/cancerous state and maintaining their differentiation.

The main risk I heard about is tissues with rapid cell turnover, but some startups are working on it.