They can, but you have to shape it a little bit so that they're out of the comfort zone and playing in a different role than their usual. It's the role, not the formal structure, that is important.

Improv acting, for example, centers simple "improv games". Playing the game imposes moments of vulnerability and creativity. But if you don't add enough context some proportion of the actors will fall into habit and "play like a winner", knocking over everyone else's boundaries by being an asshole.