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Re:Why No Roman Industrial Revolution? by felipellrocha on Friday July 28, 2023 @06:40PM (#36914343)
A ton. The Antonine plague comes to mind.
Re:Why No Roman Industrial Revolution? by mitthrowaway2 on Friday July 28, 2023 @06:42PM (#36914363)
A bit later, after the fall of the western empire, but the Plague of Justinian is another significant one.

https://en.wikipedia.org/wiki/Plague_of_Justinian