LSD helps to treat alcoholism

Re:LSD helps to treat alcoholism by gbaygon on Friday March 09, 2012 @01:53AM (#3683208)

There is something curious about LSD.

A "more than recreative" dose of 200 micrograms is still a very small dose compared with most drugs. And it will blow your head up.

According to various sources (e.g. erowid) LSD is eliminated by the liver very quickly.

So how come that the trips lasts 5-12 hs, with negligible blood concentrations?

I may very well behave as Tim Leary said a "chemical key" for certain brain circuits.

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Re:LSD helps to treat alcoholism by itmag on Friday March 09, 2012 @04:13AM (#3683476)

Ah, a fellow fan of the 8 Circuit Model. Mind emailing me? :)

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Re:LSD helps to treat alcoholism by Daniel_Newby on Friday March 09, 2012 @03:38AM (#3683420)

> So how come that the trips lasts 5-12 hs, with negligible blood concentrations?

Some drugs are very tightly bound to the receptors they target. (A few are even permanent, so the target protein has to be recycled to turn off the drug.) The blood-brain barrier serves as a one way gate that retains some drugs despite falling blood levels.

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