Recreate the cavity-preventing GMO bacteria BCS3-L1 from precursor

Re:Recreate the cavity-preventing GMO bacteria BCS3-L1 from ... by akrolsmir on Wednesday July 12, 2023 @10:23PM (#36704332)

Yeah, agreed that the proposal has a whiff of "too good to be true". The applicant's track record looks fairly good, though (he's previously invested in my startup, Manifold Markets, and otherwise has an interesting history in many different domains).

I think if there's even a 1% chance that the intervention looks as good as promised, it'd be worth further study for the proposed costs.

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Re:Recreate the cavity-preventing GMO bacteria BCS3-L1 from ... by wdwvt1 on Wednesday July 12, 2023 @10:28PM (#36704354)

I am a drug developer working on identifying novel therapeutics from human skin, oral, and intestinal bacteria.

I love the idea of Manifund - but I think this may not be the best project for it. This proposal needs some review by a biologist. In its current form, I think this is a much less impactful use of money than other things on Manifund.

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Re:Recreate the cavity-preventing GMO bacteria BCS3-L1 from ... by fbdab103 on Thursday July 13, 2023 @01:19AM (#36705282)

Curious what those would be. Again, too good to be true, but if we could vaccinate against cavities, that seems like an enormous amount of human misery eliminated for a one time investment.

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