Re:Gene linked to long Covid found in analysis of thousands ...
by matrix_overload on Wednesday July 12, 2023 @11:24AM
(#36695913)
From the first link:
Global 16326 G=0.95075 C=0.04925
European 12074 G=0.97896 C=0.02104
African 2816 G=0.9052 C=0.0948
Asian 108 G=0.630 C=0.370
So, roughly 5% of the population is affected, lower risk for European ancestry, much higher risk for Asians (37%, but the sample size is rather low).
Re:Gene linked to long Covid found in analysis of thousands ...
by causi on Wednesday July 12, 2023 @12:53PM
(#36697600)
Is the African referenced from samples from Africa or from African-Americans?
Re:Gene linked to long Covid found in analysis of thousands ...
by dekhn on Wednesday July 12, 2023 @01:51PM
(#36698759)
Africa (continent), there is a different row for African Americans. And "African (Other)"
Re:Gene linked to long Covid found in analysis of thousands ...
by aaauaucuggaa on Wednesday July 12, 2023 @11:21AM
(#36695873)
Thank you very much for sharing these links, a SNP id and browser link was exactly what I was looking for!
Re:Gene linked to long Covid found in analysis of thousands ...
by bears-n-beets on Wednesday July 12, 2023 @11:25AM
(#36695935)
Pardon my ignorance - what does it mean to have SNP rs1983891 (what pops up when I search FOXP4 in my Promethease report) but not rs9367106? I have only rs1983891(C;C).
Re:Gene linked to long Covid found in analysis of thousands ...
by oaktrout on Wednesday July 12, 2023 @11:52AM
(#36696461)
Probably no relevance to the topic at hand. This research applies only to the documented SNP.
Unrelated, you may have some increased risk for prostate cancer: https://www.snpedia.com/index.php/Rs1983891
Re:Gene linked to long Covid found in analysis of thousands ...
by qclibre22 on Wednesday July 12, 2023 @11:58AM
(#36696552)
You're probably right. Look at figure 3 in the paper. The effect is for region upstream of FOXP4. The reported Prometheus snp ( rs1983891 ) is not in this region, it is in an intron in FOXP4.
Re:Gene linked to long Covid found in analysis of thousands ...
by bears-n-beets on Wednesday July 12, 2023 @02:41PM
(#36699689)
Interesting. Glad I don't have a prostate then! :)
Preprint is at https://www.medrxiv.org/content/10.1101/2023.06.29.23292056v... .
A link to the UCSC genome browser of the location of the SNP : https://genome.ucsc.edu/cgi-bin/hgTracks?db=hg38&position=ch...
The location in question is upstream of FOXP4 and in an intron of two genes: FOXP4-AS1 and LINC01276