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Re:Gene linked to long Covid found in analysis of thousands ... by qclibre22 on Wednesday July 12, 2023 @11:02AM (#36695593)
More info: the SNP is rs9367106 ( https://www.ncbi.nlm.nih.gov/snp/rs9367106 )

Preprint is at https://www.medrxiv.org/content/10.1101/2023.06.29.23292056v... .

A link to the UCSC genome browser of the location of the SNP : https://genome.ucsc.edu/cgi-bin/hgTracks?db=hg38&position=ch...

The location in question is upstream of FOXP4 and in an intron of two genes: FOXP4-AS1 and LINC01276

Re:Gene linked to long Covid found in analysis of thousands ... by matrix_overload on Wednesday July 12, 2023 @11:24AM (#36695913)
From the first link:

  Global  16326  G=0.95075  C=0.04925
  European  12074  G=0.97896  C=0.02104
  African  2816  G=0.9052  C=0.0948
  Asian    108  G=0.630  C=0.370
So, roughly 5% of the population is affected, lower risk for European ancestry, much higher risk for Asians (37%, but the sample size is rather low).
Re:Gene linked to long Covid found in analysis of thousands ... by causi on Wednesday July 12, 2023 @12:53PM (#36697600)
Is the African referenced from samples from Africa or from African-Americans?
Re:Gene linked to long Covid found in analysis of thousands ... by dekhn on Wednesday July 12, 2023 @01:51PM (#36698759)
Africa (continent), there is a different row for African Americans. And "African (Other)"
Re:Gene linked to long Covid found in analysis of thousands ... by aaauaucuggaa on Wednesday July 12, 2023 @11:21AM (#36695873)
Thank you very much for sharing these links, a SNP id and browser link was exactly what I was looking for!
Re:Gene linked to long Covid found in analysis of thousands ... by bears-n-beets on Wednesday July 12, 2023 @11:25AM (#36695935)
Pardon my ignorance - what does it mean to have SNP rs1983891 (what pops up when I search FOXP4 in my Promethease report) but not rs9367106? I have only rs1983891(C;C).
Re:Gene linked to long Covid found in analysis of thousands ... by oaktrout on Wednesday July 12, 2023 @11:52AM (#36696461)
Probably no relevance to the topic at hand. This research applies only to the documented SNP.

Unrelated, you may have some increased risk for prostate cancer: https://www.snpedia.com/index.php/Rs1983891

Re:Gene linked to long Covid found in analysis of thousands ... by qclibre22 on Wednesday July 12, 2023 @11:58AM (#36696552)
You're probably right. Look at figure 3 in the paper. The effect is for region upstream of FOXP4. The reported Prometheus snp ( rs1983891 ) is not in this region, it is in an intron in FOXP4.
Re:Gene linked to long Covid found in analysis of thousands ... by bears-n-beets on Wednesday July 12, 2023 @02:41PM (#36699689)
Interesting. Glad I don't have a prostate then! :)