I'm aware, and in context with religion is an apt metaphor. But in context with psychedelics it's not.

They're not a numbing agents, they're catalysts for change, that's why they're applicable to therapy in ways that opiates are not.

Yes and no. At some low-level the brain doesn't differential between physical pain and mental / emotional pain. It's pain, and it needs to be reckoned with. Maybe psychedelics aren't painkillers in the opioid sense. However, they do provide pain relief, and yes perhaps an opportunity for healing.

The difference really isn't all that much.