It’s a wee bit silly given that the article has “Y chromosome” all over it. But this is an article about cancer, and one could just as easily imagine that testosterone levels, or estrogen levels, or amounts of various types of tissue, etc could affect incidence of various types of cancer.

For example, brief searching found:

https://en.m.wikipedia.org/wiki/Complete_androgen_insensitiv...

XY people with this condition have rather different cancer risk profiles than the general population of XX cis females or XY cis males.