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Re:Genetic Mutation Makes People Feel Full – All the Time by reliablereason on Sunday June 25, 2023 @07:35AM (#36467144)
> obesity, it has nothing to do with food overconsumption

You would have to deny the laws of thermodynamics to assert such a thing.

Genetics of certain individuals can favor ways of dealing with to much energy input that is not fat storage (like generating more movement or heat), but thermodynamically all time system input is balanced with all time system output.

Denying thermodynamics is not wise, the empirical evidence for it is very very strong!

Re:Genetic Mutation Makes People Feel Full – All the Time by meany on Sunday June 25, 2023 @10:15AM (#36468370)
It’s reasonable to assume that Genetics can also impact desire for consumption and for higher caloric foods.
Re:Genetic Mutation Makes People Feel Full – All the Time by reliablereason on Sunday June 25, 2023 @10:45AM (#36468688)
Genetics also effect your extraction efficiency. If a person consumes 1000 kilocalories of food as measured with a bomb calorie meter some individuals might get 4184 kilojoules of system input and some might only get 2000 kilojoules of system input.

This does however not in anyway point to some proposition where obesity is not caused by food overconsumption. It does however showcase that genes have effects that increases the statistical likelihood for some people with certain genetics to become obese. And that the threshold for food overconsumption for an individual will depend on the individuals genes. But that is not a bold new statement, another example would be that a large human will require more energy to live, their food overconsumption threshold will be at a higher energy value.

Re:Genetic Mutation Makes People Feel Full – All the Time by leaving on Sunday June 25, 2023 @10:15AM (#36468376)
You are absolutely correct, except politically.