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Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by heyitsguay on Friday June 23, 2023 @09:21PM (#36454471)
tl;dr probably from a sick animal, maybe from a lab, no smoking gun either way. Probably not engineered or lab-adapted.
Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by freitzkriesler2 on Friday June 23, 2023 @09:27PM (#36454504)
> Virus started in city with a high security biolab

> Evidence of same strain of coronavirus being studied at lab.

> CCP scrubbing virology labs internet presence.

> CCP closing said virology lab

> CCP blocking all international inquiry into said lab

> "Probably not engineered or lab adapted."

Lol, lmao even.

Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by johndotsun on Friday June 23, 2023 @09:35PM (#36454561)
The virus having been accidentally released from the lab doesn't require that the virus was modified in or by the lab between the time of leak and the time of collection.
Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by photochemsyn on Friday June 23, 2023 @09:43PM (#36454617)
No, but a virus suddenly showing up that was pre-adapted to replication in human bodies and didn't follow the usual zoonotic origin scenario of traceable series of mutations over time in both animal and human hosts, along with the sudden appearance of a furin cleavage site not found in any other relatives of said virus, points to (1) likely serial passage through human-gene-modified mice and human cell cultures and (2) CRISPR-related insertion of a human-like furin cleavage site into the adapted virus.

This kind of research is dangerous and the risks far outweigh any putative benefits. There are literally hundreds of mammalian viruses out in nature that pose zero risk to humans but which could be modified by these procedures to generate novel pandemic diseases with which the human immune system has had no prior experience.

Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by freitzkriesler2 on Friday June 23, 2023 @11:07PM (#36455089)
Great comment but the down d00ters can't handle using common sense and will happily swallow any narrative told to them by talking heads.
Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by baja_blast on Friday June 23, 2023 @10:17PM (#36454808)
> Probably not engineered or lab-adapted.

Despite having a novel furin cleavage site in the exact location as stated in a grant proposal, a furin cleavage site that happens to make the virus extremely infectious towards humans all while leaving no trace of how it adapted this feature.

This seems to me more like a desperate attempt to avoid any regulations or attention drawn to this reckless research conducted all over the world!

Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by lamontcg on Friday June 23, 2023 @10:54PM (#36455012)
A PRRA furin cleavage site that was a previously unknown sequence and not something that a scientist would have copied off some other virus.
Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by BasedAnon on Saturday June 24, 2023 @08:10AM (#36458002)
But one that could definitely emerge via gain of function.
Re:Declassified U.S. report on origins of Covid-19 virus [pdf] by lamontcg on Saturday June 24, 2023 @10:54AM (#36459184)
No, it is amazingly unlikely that you'd see an insertion like that arise through some kind of random serial passage.

In nature that happens by recombination which takes many millions of infections to emerge. In the lab you are just replicating that process by serial passage through animals where you might have a dozen animals serially infected. And the chances are probably lower because it is less likely the lab animals would wind up coinfected with another virus that would act as the source material. "Gain of function" research isn't magic.