I trust Jeff is making decent choices in his modules to support the distributions he's offering (including very similar derivatives)

By doing this, there's certainty that a lot of what's written will work just fine on RHEL. It's a huge Python library with the express purpose of abstracting away annoying OS quirks

CentOS Stream <-> RHEL is basically point releases. You're generally well past this stage by using Ansible.

At most you want to care about the OS family, treating the derivatives as part -- Debian, Red Hat, etc. Focusing mostly on binary/config file path quirks

There may be certain traits about RHEL users that will bring some issues

eg: more likely actually using SELinux, have forgotten to tend to their subscriptions, or are aiming for more strict compliance