Not sure if I'd be desperate enough to try it on a plane (the stereoscopy would probably make me sick), but as a viewing experience it's phenomenal. The OLED panel on the original Quest is a godsend for movie watching, and when streaming over DNLA I can get 3-4 hours of battery life.
It truly is a glorious viewing experience, and if you make the screen large enough you effectively get full 1080p detail.
Sometimes I've found resting the laptop in my lap/knees along the screen hinge (so it makes a 45 degree angle with my thigh) to be the most usable. This requires you to pull your shoulders/elbows back however so you usually can't do it if you have someone you don't know sitting next to you.
I have strongly debated bringing my Quest 2 onto a plane and using a wireless keyboard to program with, I think the ergonomics would work out much better when flying coach.
I hadn't thought of that. As a fairly tall person, working on a laptop or tablet on a plane has become a literal pain in the neck. I don't know if it's that the seats are closer, the tray tables are lower, or maybe I'm just getting old. This seems like a much more pleasant experience.