> a large successful enterprise system built on Smalltalk... To my knowledge no such system exists

"a fully-integrated, model-driven, automated silicon wafer fabrication facility (fab) ... ControlWorks managed fab saved TI the equivalent of 1.2 fab lines last year. What does a fab cost? roughly $1B!"

http://www.google.com/search?q=ControlWorks+smalltalk

Kapital, 70 developers in 4 locations in 2005

http://www.google.com/search?q=kapital+smalltalk

http://www.google.com/search?q=oocl+smalltalk