Wines (generally) don't use hops. Hops are such a strange flower (or weed depending on your view of hops) that provide a lot of very complex molecules that break down in interesting ways over time. At their best those molecules are flowery and subtly bitter. At their worst they break down into skunky things, some of which at extreme worsts are poisonous. Grapes have some complex molecules, but not the same sorts of bitter sulfides that hops do.