Of course there is. The "hello-world" microbenchmark tells you something about the core stack performance of the frameworks relative to one another. This tends to be surprisingly indicative of the relative real-world throughput per node that you may expect for a more complex application.

I.e. Rails (ruby) scores 4 times lower than Python in that micro-benchmark. This is pretty close to the difference that I've observed between real applications on the respective platforms. If anything you'll see the difference magnified in a complex application, but it's unlikely to turn around.

Whether that matters or not in the big picture is a different question (it usually doesn't).

I wouldn't say so. The bottleneck in a hello world benchmark might be a component of the framework, but in complex applications it's likely to be something else. Just look at the "Template Test with DB Query": There, Sqlite is the bottleneck, and the performance difference between Django and Rails fades into background completely.

Nope. Ruby/Python app-servers always end up CPU-bound, unless you're doing something very much out of the ordinary (such as blocking on an embedded SQLite...).