That wouldn't be bad, but I think you could do something more off-putting with something like deliberately slightly bad kerning.

I'm not sure of the extent to which you could use ligatures to tweak the serifs, rather than remove them completely (if possible - frustration will be maximised if the reader is unable to tell what's wrong, even after they come to believe that something is wrong).

Had the idea a while back to make posters and t-shirts with ‘I [heart] Helvetica’ on them, but set in Arial to wind up design nerds. But realised that 99.999% of anyone except possibly myself wouldn’t notice of care.

But it would ruin the day of anyone who did.

Isn't that just Arial?