Basically I removed all of the default panels and setup desktop widgets. The launcher widget is the most used. Within it I created custom launchers to open a web browser in full screen mode directed to a particular site like Netflix, YouTube, Prime Video etc. and downloaded icons for it. Other widgets I use is a task tray, weather widget, clock, external HD manager and power. I also found that I had to add the volume widget to get the volume controls on my USB remote to work for some reason.

I also configured font sizes, cursor size and mouse acceleration for usability. It works really well.