More than 99% of atoms are either Hydrogen or Helium, all other proton configurations are edge cases that are almost always irrelevant.
As with anything, you have to determine the question you are actually asking and the context you are asking it in before you can decide whether or not edge cases are relevant. Are you engineering for a satellite? You better consider the possibility of cosmic rays!
Also intersex people are astronomically more common than bit flips on earth and people with sex hormone imbalances are even more common than that.
Just asking, because some people are born with a different number of legs.
(This is not meant to imply that no consideration should be given to the exceptions, which quite reasonably it clearly is.)
All to say, I don't really care much about these claims in isolation, I care when someone says e.g. "there are two sexes, so we shouldn't let trans people transition". Those conversations are a context where edge cases, caveats, and complexities all play a huge role.
It's like running off into the weeds for a week in a computer science class because "Cosmic rays can flip bits and make true things false". Like sitting with a group of people who refuse to move forward without always acknowledging cosmic bit flip scenarios.