Sure, we have about 2,700 years of tradition speaking of souls (considering the major religions: Christianity, Islam, Buddhism, Hinduism, and Judaism). Where did those 2,700 years got us? Has any religion been able to build a conscious agent starting from basic materials (whatever they consider basic, pixie dust if they will)? Have all this years speaking of souls managed to achieve something meaningful, even as a side effect, that actually improves the quality of life? I'm talking hay [2], indoor plumbing, hook-and-loop fasteners, ibuprofen, GPS, voltmeters, extreme ultraviolet lithography, things that you and I can use and rely on daily. I have read pretty much all the major texts of the major traditions, from Mahābhārata to Summa Theologiae, call it intellectual curiosity. If not for the "bragging rights" to say that I know what filioque or bodhipakkhiyādhammā means, I would regret it, wasted time and pointless eye strain. So no, it's not nonsensical and unscientific to rule out a not even hypothesis such as the "soul" after 2,700+ years without any kind of results and absolute incompatibility with the way we actually interact with the world, scientifically or not: photons, atoms, electromagnetic fields and the like.
[1] https://en.wikipedia.org/wiki/Dissociative_identity_disorder
[2] "The technologies which have had the most profound effects on human life are usually simple. A good example of a simple technology with profound historical consequences is hay.", https://quotepark.com/quotes/1924489-freeman-dyson-like-many...
To be clear on the other things you mentioned, I think science, enlightment and all the modern technology is completely worthless, evil, and harmful. I think they only degraded the quality of life, never increased. No, I’m not living under a rock, I know Rust and JS, have a digital ocean server and some domains, have built a cell phone from scratch, eat chocolate bars, have a 3 story concrete house, am surrounded by all sorts of digital screens. I’m aware what supposed “benefits” of modernity are.
See Islam [1,2] or the book Technological Slavery by Dr. David Skrbina [3].
[1] Documentary series: https://youtube.com/playlist?list=PLcnL9bB-q3ymnRNcpZGcVVjiD...
[2] Third-party moderated debates on Islam versus Modernity: https://youtube.com/playlist?list=PLcnL9bB-q3ylQ9CZdB8YfjoDv...
[3] https://ia800300.us.archive.org/21/items/tk-Technological-Sl...
> We looked insanely deep into the brain [4], there is no magic going on.
Indeed all computation and input collection and such happen in the brain. I just don't understand how I can experience anything if I'm composed only of matter. How come there happens to be a mind? Indeed the electrochemical charges from visual receptors in the eye will be transmitted and computed and memory and dopamine and all the neurons will fire regardless of whether I'm only matter or not. But how can the experiencing consciousness, 'me' arise from matter?
> only a simulation can be conscious, not physical systems
This is what I'm talking about, only that I don't see why simulations are not physical systems.
> yes, you are electrochemical charges, we all are, what else could we be?
It's nonsensical and unscientific to completely rule out the possibility that we can be something else as well, especially when we can't study it directly, like in the example of soul.