Rapamycin: The unlucky history of the most powerful anti-aging drug

Re:Rapamycin: The unlucky history of the most powerful anti-... by garganzol on Monday May 08, 2023 @05:33PM (#35867315)

NAC is a glutathione precursor. It is both anti- and pro- cancer. It is anti-cancer in a sense that glutathione reduces the risk of getting cancer in the first place. It is pro-cancer in a sense that it reduces the power of immune response due to reduction of the amount of produced ROS, which may theoretically lead to a faster cancer spread.

So yeah, they both are kind of similar in that dimension.

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Re:Rapamycin: The unlucky history of the most powerful anti-... by tysam_and on Monday May 08, 2023 @10:45PM (#35869644)

I can't speak either way on the cancer effects, but fun fact to all reading, NAC is a great glutamate mop because glutathione is made of 3 amino acids, IIRC, and glutamate is one of them. NAC is literally just glutathione without the glutamate, and it crosses the BBB and such more easily too, I believe?

In any case, it grabs onto free glutamate, and, whammo! less glutamate, instant glutathione. quite the nifty trick.

has some interesting data/studies backing it up, and also has some great psychiatric effects as well. IIRC it's used for schizophrenia among other things.

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