Interesting stuff, glad to see that the research is continuing in this area. I'm thinking about experimenting with topical alagebrium just to see if it does anything. I recall a study in mice that found a very significant effect on skin wrinkles in aged animals.

And it's lipofuscin, I mistyped it. Basically oxidized junk molecules that never seem to get broken down and just accumulate within the cell with age. Interestingly, piracetam seems to have a positive effect on this in rodent brains.