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Re:Rapamycin: The unlucky history of the most powerful anti-... by tysam_and on Monday May 08, 2023 @03:46AM (#35859097)
Creatine for brain health is unbelievably good too IIRC (don't quote me on it though, please! ;P)

One of the hard parts of aging stuff is how nonlinear it is. A lot of the good drug treatments seem to be short term/cyclical, along with significant lifestyle modifications.

In addition to what the other commenter said, I've heard of OMAD and having a strong community/having a purpose or something to do as another strong factor in longevity, in the 90-100+ year olds in Japanese community for example. I can't remember if OMAD was correlated to that community or a different study, however.

Re:Rapamycin: The unlucky history of the most powerful anti-... by GordonS on Monday May 08, 2023 @05:12AM (#35859613)
Can you say some more about brain health, like how much creatine to take, what the expected benefits are, please?
Re:Rapamycin: The unlucky history of the most powerful anti-... by tysam_and on Monday May 08, 2023 @05:39AM (#35859757)
Here is a good article, I think my favorite part is the paragraph containing reference #146: https://www.mdpi.com/2072-6643/14/5/921