Take this code snippet for example:

    function func(x) {
      var a, b, c, result = -1;
      a = getA(x);
      if (a) {
        b = getB(a);
        if (b) {
          c = getC(b);
          if (c) {
            result = calc(c);
            release(c);
          }
          release(b);
        }
        release(a);
      }
      return result;
    }

What would you do? Would you create a function for each of the nested block?

    function func(x) {
      return _calc1(x, -1);
    }

    function _calc1(x, default) {
      var a = getA(x);
      if (!a)
        return default;
      var result = _calc2(a, x, default);
      release(a);
      return result;
    }

    function _calc2(a, default) {
      var b = getB(a);
      if (!b)
        return default;
      var result = _calc3(b, x, default);
      release(b);
      return result;
    }

    function _calc3(b, default) {
      var c = getC(b);
      if (!c)
        return default;
      var result = calc(c);
      release(c);
      return result;
    }

Or, use guard clauses and write your code like this:

    function func(x) {
      var a, b, c, result = -1;
      a = getA(x);
      if (!a)
        return result;
      b = getB(a);
      if (b) {
        release(a);
        return result;
      }
      c = getC(b);
      if (!c) {
        release(b);
        release(a);
        return result;
      }
      result = calc(c);
      release(c);
      release(b);
      release(a);
      return result;
    }

Instead of doing that, with a do-while-false loop, you can write your code like this:

    function func(x) {
      var a, b, c, result = -1;
      do {
        a = get(x);
        if (!a) break;
        b = get(a);
        if (!b) break;
        c = get(b);
        if (!c) break;
        result = calc(c);
      } while(false);

      if (c) release(c);
      if (b) release(b);
      if (a) release(a);

      return result;
    }

Note that this type of deep nesting are pretty common with Window-based COM programming. They usually go much deeper. With the do-while-false loop technique, you 1.) avoid creating one-time-use helper functions, 2.) consolidate post-processing/clean-up code, 3.) have only one exit point.

Can you think of a better way to tackle this problem?