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A comment on The Role of Diet on the Gut Microbiome, Mood and Happiness. Parent comment

Re:The Role of Diet on the Gut Microbiome, Mood and Happiness by uberduper on Wednesday April 26, 2023 @04:07PM (#35719268)
My understanding of the low carb argument here is that LDL isn't inherently bad, but oxidized LDL is and that LDL requires a high blood sugar environment for oxidation. I don't have any reason to know if that's right or wrong. I hope it's right, but I also have made efforts to avoid processed meats high in saturated fats (like salami, cold cuts) just in case.
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Re:The Role of Diet on the Gut Microbiome, Mood and Happiness by hombre_fatal on Thursday April 27, 2023 @02:14PM (#35732326)
Oxidation is what makes LDL recognizable to scavenger receptors. It's immediately eliminated from the blood.

We can actually wash our hands of LDL discussion because we have a better marker for atherosclerosis: Apolipoprotein B.

Even though LDL is a proxy for Apo B (you basically can't have high LDL and low Apo B nor vice versa), it's better to focus on Apo B which is carried by lipoproteins like LDL and is more causally linked in CVD.

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