I used to find it irritating that I had to jiggle the mouse to find the cursor, because it doesn't really stick out on screen when it is white or black and I have a lot of screen area. Then I tried turning the cursor yellow with a black border. It is great, it's obvious where it is with a glance now.

Intrigued by your comment, I've just tried it. Man, it's really working. It's really effective, I'll try to adapt to the colours and see if I keep it!