From the last time booking.com was discussed I picked up some ublock origin filters that make the website more bearable.

You can copy and paste them directly in your ublock config (ublock options -> My filters)

  ! https://news.ycombinator.com/item?id=21860328
  booking.com##.soldout_property
  booking.com##.sr_rooms_left_wrap.only_x_left
  booking.com##.lastbooking
  booking.com##.sr--x-times-booked
  booking.com##.in-high-demand-not-scarce
  booking.com##.top_scarcity
  booking.com##.hp-rt-just-booked
  booking.com##.cheapest_banner_content > *
  booking.com##.hp-social_proof
  booking.com##.fe_banner__red.fe_banner__w-icon.fe_banner__scale_small.fe_banner
  booking.com##.urgency_message_x_people.urgency_message_red
  booking.com##.rackrate
  booking.com##.urgency_message_red.altHotels_most_recent_booking
  booking.com##.fe_banner__w-icon-large.fe_banner__w-icon.fe_banner
  booking.com##.smaller-low-av-msg_wrapper
  booking.com##.small_warning.wxp-sr-banner.js-wxp-sr-banner
  booking.com##.lock-price-banner--no-button.lock-price-banner.bui-u-bleed\@small.bui-alert--large.bui-alert--success.bui-alert

Apart from these, I use some additional ublock filters to block some of their tracking that I am not ok with.

  $removeparam=/^(error_url|ac_suggestion_theme_list_length|ac_suggestion_list_length|search_pageview_id|ac_click_type|ac_langcode|ac_position|ss_raw|from_sf|is_ski_area|src|sb_lp|sb|search_selected|srpvid|click_from_logo|ss|ssne|ssne_untouched|b_h4u_keep_filters|aid|label|all_sr_blocks|highlighted_blocks|ucfs|arphpl|hpos|hapos|matching_block_id|from|tpi_r|sr_order|srepoch|sr_pri_blocks|atlas_src|place_types)/,domain=booking.com
  $removeparam=/sid=.\*;BBOX/,domain=booking.com
  ||www.booking.com/c360/v1/track
  ||www.booking.com/fl/exposed
  ||booking.com/personalisationinfra/track_behaviour_property
  ||booking.com/has_seen_review_list

Note that these may result in you receiving some higher prices by removing some referrer info. If you do see that happening, feel free to remove the offending config if the price difference is significant for you. I usually don't bother for differences of < $10 (price displayed on the search page vs the property page).