Here's an anecdote for touch vs. mouse/keyboard:
Pretty sure I'm not - nor is my family setup - typical of a windows user. We have two touchscreen desktops in our house.
I have a two year old that can work the touchscreen very proficiently. My 5 & 7 year old stick with the mouse and never use the touch, I almost never use touch, and my wife rarely uses it.
Based on my personal observations, on the desktop, touch is good for very new users or those who lack the physical coordination to control the mouse and keyboard. Otherwise, mouse and keyboard wins.
The Windows 8 mouse experience is really lacking at the moment. I expect that gets a major update in the next version.
It's like old efforts to make cars and vans run on the same body. The cars handled like vans and the vans handled like awkward cars.
If you're looking to only use a mouse, I suspect you will be spending time in Desktop mode. I know that the CTP has enhanced the mouse support in RT mode, but it's still touch-first apps. I don't like tablets and don't love the nature of touch interfaces and I know that I will not be happy with a mouse and WinRT mode ever. Frankly, if the buttons and layouts are accommodating for touch interfaces, it's NOT going to be optimal for use with a mouse. (I think some additional evidence of this would be the intrusion of ribbon into Windows Explorer. IMO it's pretty obvious that it's motivated by touch interface needs.)
In the developer preview it looked awful to have the black windows button on the aqua 3d suparbar. Why not just make the whole thing black? I think the desktop would look great with solid white / colored windows over a good photo.
Windows 8 is looking like such a failure.
It might be the same functionality, but that's not really saying much. Linux and Windows fundamentally offer the same functionality.
I think it's going to be jarring to move between classic and Metro modes, but I don't think there's a clear way for Microsoft to alleviate that. I also don't think it's unreasonable to say that there is a tablet paradigm that can live alongside the regular desktop paradigm. I think there are some that expect Microsoft Office and a twitter app to be equally usable via a mouse and a finger and I'm not sure that's entirely reasonable. At the very least, the hacker in me has no problem with needing to break out a mouse and keyboard to really get things done.