Why wouldn't it? Knowledge produces technology, technology magnifies capabilities, magnified capabilites create first- and second- order consequences that feed back on each other. Increased complexity demands increased energy to maintain, and increased catastrophe in the event of failure.

The natural world alone has disease, disaster, predators, and threats from space but would exist independent of knowledge. Technology allows us to mitigate those, and as a trade-off we get biological and chemical weapons, mass shootings, the Tsar Bomba, etc.