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Re:What is xylazine, the dangerous new drug fuelling Canada’... by atchoo on Monday April 10, 2023 @07:46AM (#35511239)
I don't think you lose much tolerance within the week or so the acute withdrawal symptoms last.

I think the danger is from relapses long after withdrawal when both tolerance and knowledge of the supply has been lost. In some ways, withdrawal is the easy the bit - brutal but something to fight that gets easier as time passes. The nagging empty hole in your soul with sobriety is harder to fill and drags you back.

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