FTL greatly complicates the Fermi Paradox. Without FTL you can make the case that large scale colonization of the galaxy is impossible or that interstellar travelers couldn’t care less for dry inner solar system worlds (though grabby aliens might have consumed Ceres or Pluto.)

With FTL you could have some situation like Guardians of the Galaxy unless our planet was deliberately cut off like the Urantia people or Free Zoners believe.