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A comment on Multiple Sclerosis Discovery Could End Disease's Chronic Inflammation. Parent comment

Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by runnerup on Friday February 24, 2023 @09:05PM (#34933045)
TUDCA is not perfectly safe. Studies show that while it does prevent damage from ethanol and AAS abuse when taken during or after, it can also cause/exacerbate damage when taken prior to ethanol/AAS or by healthy individuals.
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Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by TedDoesntTalk on Friday February 24, 2023 @10:02PM (#34933394)
What is AAS?
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Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by runnerup on Friday February 24, 2023 @10:08PM (#34933424)
Anabolic steroids, it’s popular in that community as a harm reduction supplement for liver support.
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Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by graeme on Friday February 24, 2023 @10:06PM (#34933412)
To be clear, if you’re not taking alcohol/ethanol etc then TUDCA seems fairly safe for short term use
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Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by runnerup on Friday February 24, 2023 @10:21PM (#34933499)
For <8 weeks, yes. But year-round general supplementation for no indicated reason can be harmful. TUDCA is known to lower HDL cholesterol (good cholesterol).[0]

NAC would be a more appropriate year-round liver support for general supplementation.

0: https://pubmed.ncbi.nlm.nih.gov/8674405/

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Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by graeme on Friday February 24, 2023 @10:56PM (#34933722)
Even that has issues. It can promote lung cancer growth and initiation. The gist is it is too good at keeping cells alive and keeps alive some that should have died.

https://www.science.org/content/blog-post/n-acetyl-cysteine-...

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Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by manmal on Saturday February 25, 2023 @01:52AM (#34934523)
NAC chelates metals like zinc and copper, so you got to watch out for low levels of those when supplementing NAC.
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Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by erentz on Friday February 24, 2023 @10:51PM (#34933688)
Oh that’s not good. Thanks for letting me know.
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Re:Multiple Sclerosis Discovery Could End Disease's Chronic ... by manmal on Saturday February 25, 2023 @01:55AM (#34934532)
I find GP‘s comment alarmist. Yes, use around ethanol consumption has been shown as harmful. But IMO the hepatoprotective properties should not be entirely discarded when considering this.
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