Not really. The AI was essentially "cheating" to play inhuman micro, its macro was apparently just as bad as typically expected.
I remember (from HN) some genetic algorithm explorations of optimal research/build orders that discovered novel and better combinations then-unknown to the playerbase.
And that was 10 or so years ago.
Which is more constrained than your average 4X, but not fundamentally different (resource + research + movement + combat).