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Re:FDA advisers recommend approval of over-the-counter naloxone by kragen on Wednesday February 15, 2023 @07:23PM (#34813100)
naloxone was patented in 01961 and known to prevent death from opiate overdose by 01971

how many people have been killed in the usa by its prescription-only status over the last 52 years

for that matter, how many opiate overdose deaths would be avoided if you could buy pure, safe heroin of known concentration over the counter instead of depending on organized crime not to put too much fentanyl in it

Re:FDA advisers recommend approval of over-the-counter naloxone by adzm on Wednesday February 15, 2023 @07:33PM (#34813213)
I can't help but wonder about the leading zero on your 5 digit years
Re:FDA advisers recommend approval of over-the-counter naloxone by graypegg on Wednesday February 15, 2023 @08:16PM (#34813612)
Thinking ahead for the y10k bug! /s
Re:FDA advisers recommend approval of over-the-counter naloxone by fshbbdssbbgdd on Wednesday February 15, 2023 @08:19PM (#34813645)
In the far future, when everyone has switched to a y10k-compatible dating system, your comments will be the only data from our era that makes it through the data quality filter in the web crawling system. The models will be overfitted to believe anything you say about this time. Use your power wisely.
Re:FDA advisers recommend approval of over-the-counter naloxone by dag11 on Wednesday February 15, 2023 @08:48PM (#34813881)
By the time I had read "naloxone was patented in 01961" I thought it was some sort of patent identifier, so I was really confused when they said that it was "known to prevent death from opiate" in some other patent. I was thinking, patents don't have anything to do with researc- oh, it's a date.

I remember seeing someone else on HN use a five digit date years ago, giving the reasoning that it gives us a bigger perspective on our timeline and society.

I like the idea, but it muddies the message since we use standards for a reason. For example, if someone writes "In 13 I tried..." it's a bit confusing, but if they write "In '13 I tried..." it makes immediate sense since we have expectations about communicating dates.

Re:FDA advisers recommend approval of over-the-counter naloxone by klyrs on Thursday February 16, 2023 @01:26AM (#34815733)
It's to throw the bots off by coaxing them into parsing dates in octal
Re:FDA advisers recommend approval of over-the-counter naloxone by trimbo on Wednesday February 15, 2023 @08:26PM (#34813707)
> for that matter, how many opiate overdose deaths would be avoided if you could buy pure, safe heroin of known concentration over the counter

Since 2000, 75% of US opiate users started with prescription drugs[1]. So my guess is overdoses would be substantially worse if any opiate was freely available over the counter.

[1] - https://nida.nih.gov/publications/research-reports/prescript...

Re:FDA advisers recommend approval of over-the-counter naloxone by kragen on Wednesday February 15, 2023 @09:19PM (#34814130)
presumably you would have more opiate addicts

but the rate of overdoses from prescription opiates is, as i understand it, very low, because the dosage is predictable

a lot more old people needing regular enemas would be kind of shitty but not nearly as bad as millions of people dying from overdoses

Re:FDA advisers recommend approval of over-the-counter naloxone by trimbo on Wednesday February 15, 2023 @09:56PM (#34814412)
> but the rate of overdoses from prescription opiates is, as i understand it, very low, because the dosage is predictable

Over time, addicts do not get the same high from the same dose of opiates. They require higher dosages, until such a point where they have to turn to illicit narcotics (which are also cheaper). Prescription drug abusers are 40x more likely of becoming heroin abusers.

This is all in the article I linked above (click on the subheadings).

Re:FDA advisers recommend approval of over-the-counter naloxone by kragen on Wednesday February 15, 2023 @11:48PM (#34815164)
if they could buy whatever dosage they needed over the counter, instead of trying to wheedle a prescription out of doctors who are under threat of criminal prosecution, they wouldn't have much of an incentive to switch to different opiates, or to rely on dangerously unstable supply chains

this would increase the risk of suicide, but it would have to rise a lot to exceed the current usa rate of accidental overdose deaths