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Re:FDA advisers recommend approval of over-the-counter naloxone by cwkoss on Wednesday February 15, 2023 @07:03PM (#34812885)
Several societies (incl France) offer codeine over the counter and have much lower opioid usage rates.

I think there would be a lot of benefit to legalizing at least one molecule in each drug class for OTC recreational use, chosen based on harm reduction standards like toxicity, therapeutic index, and duration. I think so much of the drug war's ills could be headed off by making codeine and vyvanse OTC - destroying demand for dirtier more dangerous drugs would do enough good to offset the increased abuse rate for these particular chemicals.

Re:FDA advisers recommend approval of over-the-counter naloxone by runnerup on Thursday February 16, 2023 @06:10AM (#34817300)
Vyvanse might be tough to OTC. It's still quite possible to get increasing need to take more and more and get psychosis.