It is not a big deal. Ioannidis has been peddling basically the same study for years now. He put his reputation on the line in the early weeks of the pandemic by making some very badly thought out predictions. He believed the pandemic would kill a total of 10k people in the US, and basically ridiculed the people who thought it would be even as serious as the flu.

Since then, he has been trying to convince people that he really was right all along, and basically nobody died just like he predicted.