My favorite use case for it is a hotkey to autofill my username and password for Zwift. Zwift is a cycling app that I'm only interacting with while I'm sitting on my bicycle (on a trainer indoor)

I have 0 patience for entering a password... I'm sitting there in spandex with a fan blowing in my face and I'm holding a wireless keyboard. Anything more than Ctrl+Alt+1 is too mcuh work