The one I use for quick one of conectios is:
screen /dev/ttyS1 300
or
screen /dev/ttyS0 300,cs8
My cheatsheet: screen /dev/ttySX baud_rate,cs8|cs7,ixon|-ixon,ixoff|-ixoff,istrip|-istrip
But I am heavy screen/tmux user so its natural to me.
*I believe GTKTerm has GUI for setting that up
I'm sorry to have offended you. My comment got plenty of upvotes, so it was appreciated by its intended audience.
It is easy to set baud rate and other parameters with stty, but I'll stop trying to be helpful now.
Having a dev node serial device isn't very helpful in itself if you can't easily set the baud rate and other parameters when doing I/O.
Linux Desktop might be more popular if it didn't have such condescending advocates.