Re:Making chloroform so I can sleep better at night
by FPGAhacker on Tuesday January 24, 2023 @08:18PM
(#34513061)
"Why Microwave Assisted Reactions in DMSO are a Dangerous Idea"
-- by chatGPT
Microwave assisted reactions in DMSO (dimethyl sulfoxide) have become increasingly popular in recent years as a way to speed up chemical reactions. However, there are several reasons why this method should be used with caution, especially when it comes to safety and health concerns.
One of the main dangers associated with using DMSO, and other polar aprotic solvents such as DMF and DMAc, is their ability to dissolve and transport small molecules through the skin and into the bloodstream. These solvents can permeate through traditional protective barriers like nitrile, vinyl, and latex gloves, making them ineffective in protecting the user from potential harm.
When working with these solvents, it is crucial to match the glove to the solvent. Aliphatic polymers such as LDPE or laminates like mylar (aluminized polyester) are recommended for strong solvents like DMSO to provide adequate protection.
Furthermore, DMSO is highly flammable, which can be a significant safety hazard when heated in a microwave. The high temperatures generated by the microwave can cause the DMSO to break down and release toxic fumes, which can be harmful to both the experimenter and the environment.
Microwave assisted reactions in DMSO (dimethyl sulfoxide) have become increasingly popular in recent years as a way to speed up chemical reactions. However, there are several reasons why this method should be used with caution, especially when it comes to safety and health concerns.
One of the main dangers associated with using DMSO, and other polar aprotic solvents such as DMF and DMAc, is their ability to dissolve and transport small molecules through the skin and into the bloodstream. These solvents can permeate through traditional protective barriers like nitrile, vinyl, and latex gloves, making them ineffective in protecting the user from potential harm.
When working with these solvents, it is crucial to match the glove to the solvent. Aliphatic polymers such as LDPE or laminates like mylar (aluminized polyester) are recommended for strong solvents like DMSO to provide adequate protection.
Furthermore, DMSO is highly flammable, which can be a significant safety hazard when heated in a microwave. The high temperatures generated by the microwave can cause the DMSO to break down and release toxic fumes, which can be harmful to both the experimenter and the environment.