Re:Two research teams reverse signs of aging in mice
by anovikov on Sunday January 15, 2023 @04:11AM
(#34387994)
Why didn't that experiment start with real old mice? And reversed their age to young again? That could be more convincing that "reversing" ageing of artificially aged mice.
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Re:Two research teams reverse signs of aging in mice
by tee_0 on Sunday January 15, 2023 @11:25AM
(#34390565)
Because they haven’t reversed aging in this experiment and the partial reversal they did achieve was using tools that already exist. The point of the experiment was to prove that epigenetic information loss is the cause of aging. The next step is to figure out how to completely reverse epigenetic information loss.
Re:Two research teams reverse signs of aging in mice
by epicureanideal on Wednesday January 18, 2023 @07:06PM
(#34434954)
Sounds theoretically possible. I mean it definitely happens at conception, and methylation happens at specific sites where it should, and not where it shouldn’t. So there should be a mechanism.
Even if it’s trickier than that, there are probably lots of ways to selectively restore the epigenetic information in specific patterns or specific sites that might help chip away at disease.
Somewhat related link from quick googling:
https://www.sciencedirect.com/science/article/pii/S002192582...