Re:U.S. Cancer Death Rate Has Dropped by a Third Since 1991
by docdendrite on Thursday January 12, 2023 @03:20PM
(#34359730)
HPV isn't correlative, it's causative. Additional co-transformation factors may be required, but it is well understood that E6 and E7 proteins directly lead to tumorigenesis. EBV pathogenic mechanisms are more autocrine and therefore a muddier picture, hence correlative.
HPV is merely correlative, as well. That's basically how all endogenous cancers work. With Epstein-Barr Virus the association is quite strong, though the incidence of EBV-induced cancers doesn't seem to be quite as large as HPV--~1% vs 2-3%.