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Re:Not-Such-Better-Living Through Chemistry by mypalmike on Saturday January 07, 2023 @11:42AM (#34289723)
"accumulated tolerance and long term damage from drug abuse had blunted their response"

The succinct term for this phenomenon is "chasing the dragon".

Re:Not-Such-Better-Living Through Chemistry by xrd on Saturday January 07, 2023 @12:04PM (#34290017)
First heard that term in the movie "Killing Zoe." Takes me back.