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Re:The ‘breakthrough’ obesity drugs that have stunned resear... by milleramp on Wednesday January 04, 2023 @04:31PM (#34252016)
I wonder how breaking old habits and establishing new habits over a year or so would stop a serious rebound?
Re:The ‘breakthrough’ obesity drugs that have stunned resear... by linsomniac on Wednesday January 04, 2023 @04:40PM (#34252167)
It is, in my personal experience, all to easy to fall back into the old habits.
Re:The ‘breakthrough’ obesity drugs that have stunned resear... by j33zusjuice on Wednesday January 04, 2023 @05:14PM (#34252651)
No doubt. The old habits are easier. It’s way easier to order in food and lay in bed than to cook and workout. Of course, it’s overly reductionist to assume weight loss is as easy as “stop laying around, eat healthy, and exercise.”

It kind of is that simple, but there are so many factors that help prevent us from good habits. I think my biggest issue is that food is one of the few things in my life that’s ever evoked a positive response for me. I’ve gone years without being fat, but it comes back because of some issue I encounter, and I lack the tools to deal with it in a better way. So I get depressed and eat, and eventually hate myself for falling apart again, and so we go, forever and always.

Re:The ‘breakthrough’ obesity drugs that have stunned resear... by paulpauper on Wednesday January 04, 2023 @04:48PM (#34252296)
The low success rates of diets suggest very hard to establish new habits
Re:The ‘breakthrough’ obesity drugs that have stunned resear... by s1artibartfast on Wednesday January 04, 2023 @04:57PM (#34252444)
Many things are hard, but that does not mean they should not be done.
Re:The ‘breakthrough’ obesity drugs that have stunned resear... by Robotbeat on Wednesday January 04, 2023 @05:07PM (#34252571)
Problem with diets is that your body responds to this new habit by panicking, thinking you’re going through a famine and reduces metabolism to compensate for reduced caloric intake while increasing hunger. It’s like if you’re he body responded to brushing your teeth every day by making you obsess over caramel corn. Most habit changes don’t have this “body actively fighting you with increasing ferocity” effect that caloric restriction does.
Re:The ‘breakthrough’ obesity drugs that have stunned resear... by s1artibartfast on Wednesday January 04, 2023 @07:22PM (#34254034)
Good diets are simply a healthy human diet, which should not send your body into panic after an adjustment period.

This is similar to exercise. You body goes through a period of panic and resistance.

This is why consistency is important for both diet and exercise, so you dont have to struggle and battle to rebuild the habit.

Re:The ‘breakthrough’ obesity drugs that have stunned resear... by Robotbeat on Wednesday January 04, 2023 @09:22PM (#34255090)
But what if your “good diet” DOES send your body into a panic? That is, physiologically, what occurs with many obese people when they lose weight, REGARDLESS OF WHICH DIET THEY PICK.
Re:The ‘breakthrough’ obesity drugs that have stunned resear... by s1artibartfast on Wednesday January 04, 2023 @10:09PM (#34255387)
Keywords were "after adjustment period". Your body will Panic if you quit smoking, alcohol, or many hard drugs. That doesn't mean it's a bad idea to do so.

Your body will also panic if you start working out vigorously, confront hard but necessary situations, or many other aspects of human life.

If a prescription help someone make a productive transition, that's great. My point is simply that I'm cautious of potentially lifelong crutches to avoid making difficult changes, and there's value in cultivating the ability to maintain your personal homeostasis if you can

Re:The ‘breakthrough’ obesity drugs that have stunned resear... by Robotbeat on Thursday January 05, 2023 @09:47AM (#34260263)
Again, with the idea it’s just a willpower thing to overcome some hurdle. The “panic period” is permanent for many obese people. There’s literally no end to fighting your body once you’ve lost substantial weight, it’s ALWAYS trying to lower metabolism and increase hunger to compensate. It’s not a few months and then you’re good, it’s forever. This is why a treatment like this is so necessary.
Re:The ‘breakthrough’ obesity drugs that have stunned resear... by pessimizer on Wednesday January 04, 2023 @05:05PM (#34252549)
If there are easy alternatives with the same outcomes, hard things absolutely should not be done (unless you're practicing for an emergency situation where the easy thing is not available.)
Re:The ‘breakthrough’ obesity drugs that have stunned resear... by s1artibartfast on Wednesday January 04, 2023 @07:42PM (#34254231)
Even in a utilitarian framework, there is more to consider besides outcomes, such as costs.

Examples of costs could be be the reoccurring monetary cost for the rest of your life, and being dependent on the supply of medicine to maintain your health.

Additionally, there are personal advantages to being an individual that is capable of doing and regularly practices "hard things".

Re:The ‘breakthrough’ obesity drugs that have stunned resear... by KirillPanov on Wednesday January 04, 2023 @05:56PM (#34253165)
I think the big lesson from Semaglutide is that bad eating habits are not the primary cause of obesity. More likely they are correlated due to common causation.