Yeah that. There’s something even more subtle. Experiments run with certain older lines just… failed more. It’s weird. The supervisor would say, “Yeah go to X’s lab and grab theirs.”

Like the reproducibility is contingent on so many factors. Very depressing and tedious.

There’s definitely a lot we don’t know and the knowledge gap is huge. And even if it can be done in the lab, translating some finding to a workable therapeutic is another story.