IIRC CS6 was the last non-subscription version. It's installer is 32bit but MacOS no longer runs 32bit executables. Maybe people find workarounds.

This kind of thing is especially true in iOS where every OS release kills off a bunch of software using deprecated and then deleted APIs.

It's likely in 2-3 years MacOS will pull out Intel support (like they pulled out PowerPC support after so many years when they switched to Intel)